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[Job Listings] Clinical/Data Analyst/Scientist openings at Bracket

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Senior Clinical Scientist


Position Overview:
The Clinical Scientist designs and executes clinical services to enhance clinical trials. The Clinical Scientist partners with the sponsor clinical representatives to ensure appropriate project definition and ensures that clinical deliverables are in accordance with project scope. The Clinical Scientist directly participates in attendance at face-to-face and virtual training events, and may participate in business development opportunities.

Essential Duties and Responsibilities:Other duties may be assigned.

Clinical Responsibilities
·         Collaborates with study sponsors to establish appropriate project definition
·         Reviews protocol/CRF and provides feedback as appropriate
·         Designs and ensures appropriate execution of project specific processes and data review methodologies; ensures appropriate training
·         Ensures development of appropriate clinical content (e.g., qualification methodologies, didactic presentations) for rater training and qualification programs for study staff in clinical trials
·         Evaluates data submitted in accordance with Endpoint Reliability programs and contacts raters, as appropriate, to gather additional information and provide feedback
·         Ensures that project clinical deliverables are in compliance with quality control standards
·         Proactively identifies and escalates potential project issues appropriately to project team, sponsor and/or manager
·         Communicates with study site staff in accordance with project specific methodology/SOPs and documents interaction in the respective IT application
·         Ensures compliance with quality assurance as outlined in SOPs/Clinical Operations Guidelines
·         Ensures consistency of product with actual project scope and resolves ambiguities in collaboration with both internal and external project teams
·         Monitors performance of external Clinical Experts

Management (Team Lead Only)
·         Provides direct line management to Clinical Scientist I/II, Clinical Specialist, Clinical Associate, Sr. Project Assistant, and/or Project Assistant
·         Conducts appropriate supervisory meetings, and monitors productivity
·         Ensures appropriate training and career progression

Business Development
·         Participates in business development opportunities as assigned (e.g., client meetings, bid-defenses, preparation of materials)
·         Attends conferences and scientific meetings as appropriate

Administration
·         Submits weekly report of activity to manager
·         Participates in orientation and training of staff as appropriate
·         Participates on committees as assigned
·         Completes required trainings in a timely manner
·         Enhances the Bracket’s Client Services business model by institutionalizing business processes, implementing best practices, templates, and seeking ways to work more efficiently
·         Ability to perform all responsibilities of Clinical Scientist II, if required

Skills & Competencies

Education
·         Masters Degree, M.D., Ph.D., Psy.D, Pharm.D., in healthcare-related field, with three years of clinical experience, which includes administration of psychiatric and/or cognitive scales OR
·         RN with four years of clinical experience, which includes administration of psychiatric and/or cognitive scales

Experience
·         Minimum of one year as successful Clinical Scientist II or equivalent

Personal Attributes
·         Excellent writing skills
·         Demonstrated strong analytical, organizational, creative problem solving and communication skills
·         Ability to succeed in a fast-paced, entrepreneurial environment
·         Basic knowledge of statistics
·         Competency conducting patient interviews
·         Comfortable with being videotaped
·         Competency working with data and numbers
·         Good negotiation and diplomacy skills
·         Successfully manages own time, proactively identifies and prioritizes multiple tasks
·         Ability to work with staff at all levels and across various disciplines
·         Excellent computer skills including Word, Excel and PowerPoint
·         Fluency in English (will be required to write, speak and understand English to conduct day-to-day business)
·         Detail oriented
·         Willingness to travel
·         Willingness to maintain flexible schedule

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Position Title: Data Analyst II

Department:  Technical Delivery / Product Development
Reports To (Title):  Senior Manager, Manager, Team Lead
FLSA Status (exempt or non-exempt):  Non-exempt           

Position Overview:
The Data Analyst II is responsible for working with the Technical Delivery / Product Development staff to process data changes

Essential Duties and Responsibilities:
Note:  Other duties may be assigned.

·         Responsible for executing data change and data transfer requests.
·         Periodic database exports and transfers to client based on a pre-determined subset of the structure and content.
·         Writes and executes planned and ad-hoc SQL or SAS queries against MS SQL Database to extract data for Data Transfers and Reports.
·         Creates and executes Data Change Guides (DCGs) and determines corresponding risk/impact assessments.
·         Provides Data Transfers/Reports per approved Data Transfer Specifications.
·         Reviews, provides feedback and approves Data Transfer Plans and final Data Change Form documents submitted to clients.
·         Creates stored procedures to manipulate data for data-driven changes to IVR system functionality.
·         Creates DTS packages for imports into study databases.
·         Participates in special data-related projects as needed.
·         Demonstrate extreme attention to detail and organization in all aspects of work.
·         Follow Bracket Standard Operating Procedures for data change management, data transfer verification and risk/impact assessment documentation.
·         Some technical support after-hours, on-call time may be needed.
·         Other project work and responsibilities as required.

Skills & Competencies

Education
·         2-4 years of experience working in a data-driven environment.
·         In-depth working knowledge of Structured Query Language (SQL), as well as Microsoft Windows 2000/2003/XP and the suite of Microsoft Office applications.
·         Experience with standard data mining and data presentation techniques.
·         Proven ability to handle multiple competing priorities in a fast-paced work environment with minimal direct supervision.

Competencies & Personal Attributes
·         Must have excellent written communication skills, including the ability to effectively document procedures, processes and results.
·         Demonstrated ability to meet deadlines & multi-task in a fast-paced work environment.
·         Demonstrate extreme attention to detail and organization in all aspects of work.
·         Must have very strong skills with Microsoft Office applications.
·         Must be comfortable working with business users and technical teams.
·         Familiarity with SQL Queries is a plus.
·         Working knowledge of Visual Basic is a plus.
·         Familiarity with GCP and 21 CFR Part 11 is a plus.



Position Title:  Project Specialist, Client Services     


Department:  [eClinical or Scientific] Delivery Services
Reports To (Title):  Associate Project Manager, Project Manager or Sr. Project Manager, Client Services
FLSA Status (exempt or non-exempt):  Exempt                   

Position Overview:
Management and administration of projects at assigned pharmaceutical clients.  The projects will include clinical data quality services (e.g., EDC, ePRO, IxRS, rater training, endpoint reliability, scale management, cognition, etc.) for said pharmaceutical clients.

Essential Duties and Responsibilities:
Note:  Other duties may be assigned.

Data/Site Management (70%)
·         Manage identification and resolution of clinical trial data inquiries/data changes and communication to internal and external multi-function resources within project teams
·         Manage communications with client (e.g. pharmaceutical sponsor, CRO) and site personnel regarding site/study details
    • Facilitate weekly data review meetings with clinical trial study team leaders
·         Own in-study/maintenance transactional project activities throughout entire project lifecycle, e.g.  project variable fees, inter-department workflow assignment, issue escalation
·         Prepare study materials, including system requirements, data transfer documentation, questionnaires, rater experience surveys, response sheets, and other documents as required
·         Set up master systems, additional study hardware, study site folders, and data folders for clinical trial execution
·         Coordinate and set-up data for system launch as assigned
·         Design and configure unique project systems and manage data for each assigned project, utilizing proprietary IT applications (e.g. RDA, IR2, CDR PRISM, etc.)
·         Produce data reports (e.g., weekly, interim, final, etc.) for submission to pharmaceutical clients
·         Facilitate the closedown and archival of system databases
Training Event Management (15%)
·         Attend international large scale training events (e.g. Investigator’s Meetings, Phase I site staff training) and facilitate training sessions (requires frequent overnight domestic and international travel)
·         Coordinate with clients, vendors, and expert consultants to ensure all logistics, materials, and technologies necessary for successful training events are in place
·         Independently facilitate virtual training sessions (e.g. LiveMeeting) including attendee registration, training execution and issue resolution
Administration (15%)
·         Oversee project QC activities to ensure compliance within the enterprise Quality Management System
·         Work within project team to develop and implement processes for projects
·         Prepare and maintain in-study project plans, data management plans and study binders which will be executed in collaboration with Project Managers
·         Provide weekly status reports documenting project activities, planned steps and issues
·         Track monthly and quarterly metrics (variable fee budgetary items) and provide to Project Manager for invoicing
·         Training and development of teammates as appropriate
·         Leverage Project Assistant pool resources as required by project management
·         Enhance the Bracket business model by institutionalizing business processes, implementing best practices, templates, and seeking ways to work more efficiently
·         Contribute to the development, enhancement and testing efforts for enterprise IT applications (e.g. EDC, ePRO, IxRS, RDA, IR2, PRISM, CDR System, etc.)

Experience
·         Demonstrated proficiency as Senior Project Assistant or equivalent experience for a minimum of six (6) months

Skills & Competencies

Required Skills
·         College degree (B.S., B.A.)/University Degree for EU candidates or equivalent years of experience
·         Demonstrated analytical and organization abilities coupled with good client relationship skills
·         Exceptional customer service orientation
·         Demonstrated proficiency with computers, especially Microsoft Office (Excel, Access, Word, PowerPoint)
·         Fluency in English (will be required to write, speak and understand English to conduct day-to-day business.)
·         Ability to travel for business trips (overnight business trips expected monthly)
·         Ability to work independently and proactively in a small team environment with a strong attention to detail
·         Comfortable working in a fast-paced, changing environment
·         Flexible working style

Preferred skills:
·         Understanding of pharmaceutical clinical development and/or sales & marketing
·         Background in Pharmaceutical, Medical education and/or CRO

Job Listing: Client Support Specialist – Boston, Promega

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Client Support Specialist – Boston

 Job Description:

JOB OBJECTIVE:        The Client Support Specialist will serve as the liaison to our internal and external customers.  Provide technical support and information about Promega products and services, thereby building strong customer relationships that will lead to an increase in information exchange, technology acquisition, and economic interaction.  Responsible for coordination of all end user-defined activities in their respective territories, including assisting distributors.
All times are in Eastern Daylight Time.

Job ID 
2016-1284
# of Openings 
1

Posted Date 
4/13/2016
Category 
Sales

Location : City 
Virtual

More information about this job (click here):

ESSENTIAL DUTIES:
  1. Use Sales Analysis and designated CRM to generate reports, manipulate data and effectively analyze results.  Maintain appropriate notes in the designated CRM.
  1. Identify and maintain strategic accounts and clients to maximize effectiveness.  Consistently request, receive and leverage customer referrals.
  1. Develop and maintain an active sales funnel of opportunities across the Promega product portfolio.
  1. Provide technical support by thorough knowledge of Promega’s product line and effective communication of applications related to the products.
  1. Support and develop strong customer and distributor relationships by acting as a liaison between the customer and various departments at Promega.  Bring field issues and complex sales opportunities to the regional manager and provide necessary customer follow up.  Identify both new technologies/products and “targeted” technologies/products that will benefit Promega’s business efforts.
  1. In cooperation with the Regional Manager, design and implement a coordinated business plan for the territory that reflects Promega’s corporate initiatives while taking into consideration the customer situation (funding, technology needs, etc)
  1. Work with the regional manager to develop opportunity based pricing strategies at accounts (quotes, purchasing contracts with discount schedules, freezer programs and stockroom/consignment).  In conjunction with the Promega business units, organize and conduct field-marketing activities such as workshops, focus groups and beta test programs to gain customer feedback.
  1. Remain familiar with competitive products for the purpose of educating customers on the benefit of Promega technology.  Monitor the competition  and report important activites (technical developments, trends within key accounts, seminars, training sessions, etc) back to Promega.
  1. Drive awareness and success of the Helix program through Helix stocking and sample follow up.  Host Helix relaunch parties, develop stock customization, work with the SBU to appropriately market the unit within the account.
  1. Work with SBU resource/Inside Sales Team/CAM to provide instrument demonstrations with the goal of moving opportunities forward.
  1. Discuss relevant market investment activities and playbook items for strategic territory development with the regional manager on a regular basis and enact plans to achieve goals as defined in conjunction with the regional manager.  Succinctly deliver account and territory plan presentations to the sales team at regional meetings.
  1. Flexible in handling change, meeting a standard of excellence, persistent in pursuing goals despite obstacles and setbacks.  Self-awareness of how behaviors can affect our colleagues.
  1. Understands and complies with ethical, legal and regulatory requirements applicable to our business.
OCCASIONAL DUTIES:
  1. Attend Sales Training sessions for Miller Heiman and Spin Selling.  Independently develop SPIN call plans and identify appropriate use.  With manager assistance fill out and review Blue/Green sheets and sales call plans.
  1. Represent Promega at conferences, shows, workshops and seminars locally, regionally or nationally, as necessary.  Organize and plan lectures, vendor shows, workshops and seminars in specific territory.
  1. Participate in organization for regional and national sales meetings including logistics, food, etc.
MANDATORY QUALIFICATIONS:
  1. BS or BA (MS, or Ph.D. preferred) degree in a life sciences related discipline.
  1. Technical competency to understand and to clearly discuss fundamental theory and principles of experimental design, techniques and results; to stay current in technical knowledge; to troubleshoot and to provide information back to the customer in a helpful, courteous, positive and professional manner.
  1. Minimum of 2 years lab experience with proven knowledge and understanding of molecular biology, cell biology and related fields.

Job Posting: Scientist/Snr Scientist in various areas at C4 Therapeutics

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Here is the mission of C4 Therapeutics:

C4 Therapeutics is developing a new class of targeted protein degradation (TPD) therapeutics for the treatment of a broad range of diseases. Our Degronimid™ platform incorporates highly selective small molecule binders to target disease-causing proteins and facilitate their rapid destruction and clearance from the cell through the natural ubiquitin/proteasome system (UPS). Because of this distinctive mechanism, Degronimids are capable of hitting many more targets, including those previously thought to be undruggable, while reducing the potential for drug resistance. The broad applicability of Degronimids, and our chemical biology platform designed for accelerated validation, have the potential to make an unprecedented impact across many diseases through multiple industry collaborations as well as proprietary programs.

Scientist/Senior Scientist in Medicine Chemistry

Responsibilities:

  • Develop and execute synthetic routes of target molecules, including work up, purification, isolation, and characterization of products.  Develop scalable routes of preclinical drug-candidates.
  • Optimize drug candidates through interpretation of complex data sets through iterative SAR.
  • Utilize computational approaches, including structure guided drug design, to optimize chemical leads.
  • Work with a multidisciplinary groups to initiate and advance drug discovery programs.
  • Manage external study execution at contract research organizations and engage with extramural industry and academic collaborators.
  • Contribute to the writing of patents, scientific presentations, and publications
  • Critically analyze data and communicate findings effectively to multidisciplinary team members and senior management.

Qualifications:

  • Ph.D. in organic or medicinal chemistry.
  • Minimum of 5 years of relevant experience, preferably in the biopharma/pharma setting.
  • Proven scientific track record of advancing small molecules through stage gate milestones from HID through candidate selection.
  • Expertise in synthetic organic chemistry, including methodologies, transformations, and mechanisms.
  • Demonstrated expertise in multi-step synthesis and strong knowledge of techniques related to purification and characterization of organic compounds (NMR, MS, HPLC, etc.).
  • Ability to interpret complex datasets to optimize chemical leads through SAR.
  • Ability to work independently and apply experience and knowledge to solve difficult synthetic challenges and provide useful guidance to other chemists on the project team.
  • Strong motivation, independence, and ability to work in a high-pace multidisciplinary, matrix environment with minimal supervision.
  • Demonstrated ability to effectively manage and mentor research staff.
  • Excellent interpersonal as well as oral and written communication skills required.

Interested candidates: Please send your resume, CV and any supplemental materials to careers@c4therapeutics.com

Scientist/Senior Scientist in In Vitro Pharmacology

Responsibilities:

  • Develop, validate, implement and execute biochemical and biophysical assays for medium and high throughput screening to support target identification and lead optimization for small molecule drug discovery.
  • Implement novel in vitro screening strategies and design screening and counter screening funnels to evaluate affinity, potency, and mechanism of action of drug candidates.
  • Monitor assay quality and troubleshoot issues with assay performance.
  • Work with a multidisciplinary groups (Biology, Medicinal Chemistry, and Pharmacology) to initiate and advance drug discovery programs.
  • Critically analyze data and communicate findings effectively to multidisciplinary team members and senior management.

Qualifications:

  • Ph.D. in Biochemistry, Pharmacology or a related field.
  • Minimum of 5 years of relevant experience, preferably in the biopharma/pharma setting.
  • Proven scientific track record in the development and execution of both biochemical and cell based assays to support drug discovery.
  • Demonstrated knowledge of biochemical and biophysical assay formats and readouts.
  • Strong motivation, independence, and ability to work in a high-pace multidisciplinary, matrix environment with minimal supervision.
  • Strong problem solving skills.
  • Demonstrated ability to effectively manage and mentor research staff.
  • Excellent interpersonal as well as oral and written communication skills required.

Interested candidates: Please send your resume, CV and any supplemental materials to careers@c4therapeutics.com

Scientist/Senior Scientist in Drug Discovery

Responsibilities:

  • Independently design and execute experiments to advance small molecule drug discovery programs.
  • Identify and implement target- and cell-based assays to identify/validate compound mechanism of action, inform on target and pathway modulation, and inform on cellular response to target inhibition.
  • Work with a multidisciplinary groups (Medicinal Chemistry, Biochemistry, and Pharmacology) to initiate and advance drug discovery programs.
  • Manage external study execution at contract research organizations and engage with extramural industry and academic collaborators.
  • Critically analyze data and communicate findings effectively to multidisciplinary team members and senior management.

Qualifications:

  • Ph.D. in Biology or a related field.
  • Minimum of 5 years of relevant experience, preferably in the biopharma/pharma setting.
  • Knowledge of drug discovery from target identification through clinical candidate selection.
  • In depth knowledge of oncology targets and molecular pathways and the ability to translate this knowledge into drug discovery and development endpoints.
  • Strong motivation, independence, and ability to work in a high-pace multidisciplinary, matrix environment with minimal supervision.
  • Experience working with academic collaborators and contract research organizations is preferred.
  • Strong problem solving skills.
  • Demonstrated ability to effectively manage and mentor research staff.
  • Excellent interpersonal as well as oral and written communication skills required.

Interested candidates: Please send your resume, CV and any supplemental materials to careers@c4therapeutics.com